Research Associate II: Spatial Technology Platform
Cambridge, MA 
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Posted 18 days ago
Job Description

Job Description

The Broad Institute of MIT & Harvard, a world leader in genetic research, is looking for an exceptional candidate to join the Spatial Technology Platform (STP). The STP utilizes cutting-edge spatial profiling methods to generate comprehensive, high-throughput, and multi-modal data sets at single-cell resolution. Our focus lies in highly multiplexed in situ proteomics and transcriptomics, alongside optical barcoding technologies for in situ screening and high-dimensional functional profiling such as all-optical electrophysiology. Our research efforts are directed towards understanding the dysregulation of gene-phenotype interactions in psychiatric disorders and the role of cell-cell interactions in the development and progression of cancer and immunological diseases. We are a growing team of academic researchers and professional scientists with diverse expertise in experimental biology, engineering, and computer science, fostering a collaborative and innovative environment.

The Spatial Technology Platform seeks a highly motivated individual to join our team and partner with our researchers in implementing and advancing emerging imaging- and sequencing-based spatial transcriptomic and other image profiling methods. We value strong teamwork, clear communication, and independent initiative. While the role offers daily autonomy, you'll benefit from close mentorship and guidance from our senior researchers.

The Broad Institute fosters a vibrant and intellectually stimulating research environment with deep connections to leading academic institutions throughout the Boston area. This unique ecosystem provides you with exceptional opportunities to collaborate with renowned researchers, engage in pioneering scientific inquiry, and contribute to knowledge with the potential for global impact.

KEY RESPONSIBILITIES

  • Implement imaging spatial profiling methods from start to finish (tissue prep through imaging) for 10X Xenium and Visium HD, Vizgen MERSCOPE, Slide-seq, and Slide-tags, as part of STP's mission to support researchers within the Broad Institute and in the outside community

  • Engage with collaborators and users to discuss results, troubleshoot issues, and plan next steps

  • Troubleshoot to resolve problems that may arise during tissue prep or imaging

  • Participate in new technology evaluation and implementation as part of STP's mission to develop and innovate new spatial profiling methods

  • Document, compile, and analyze experimental data

  • Attend and present at team meetings to share results and ensure that projects support team goals

QUALIFICATIONS

  • Bachelor's or Master's degree with at least 2 years of related work experience

  • Experience in molecular biology, biochemistry, biotechnology, or a related field.

  • Strong wet lab skills are required, experience with tissue processing and computational analysis is a plus.

  • Great teamwork skills, including the ability to engage with external collaborators

  • Highly independent and resourceful.

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Broad culture:
We pride ourselves on being creative and forward-thinking not only in the way we approach our science but also in the way we support our people.

Check out a sampling of our benefits:

  • 3 weeks of vacation within the first year, 13 paid holidays plus an annual winter closing from Christmas to New Year's

  • Fully covered vision exams as well as coverage for corrective lenses at no additional premium.

  • Commuter passes subsidized at 50%

  • Tuition reimbursement up to $5,250 per calendar year

  • Free on-site yoga, meditation, and boot camp

  • Regular seminars and discussion groups hosted by our BroadLife office to help you deal with a diverse array of work-life issues and make it easier to integrate work, personal, and family commitments

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

#LI-ONSITE

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Check out this video for a look into our community!

 

Job Summary
Company
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Education
Bachelor's Degree
Required Experience
2+ years
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