The Broad Institute of MIT & Harvard is looking for a Research Associate II to join the therapeutic group at the Stanley Center for Psychiatric Research. The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Based on unprecedented insights into the genetic bas

Apply computational methods to discover and analyze structural variation from long read sequencing of large human genome cohorts. Perform quality control assessments with a deep understanding of the data and the underlying biology. Develop new computational methods and improve existing methods for genomics analyses. Present results to both computational and non computatio

for the role Work in close collaboration with multiple labs, most especially those of Drs. Macosko and Stevens, to develop and execute experimental plans; Directly supervise a multidisciplinary team of researchers responsible for generating foundational datasets for the initiative; Lead regular meetings with industry partners participating in the new initiative; Manage hig

Description & Requirements At the Broad Institute of MIT & Harvard broadly and within the Neale Lab specifically, we leverage statistical and software techniques to understand the mechanisms of disease from extremely large datasets generated by scalable sequencing technologies. The lab and Institute are entering an age of one million sequences, millions of transcriptomes,

Description & Requirements Are you a passionate, invested software engineer who wants to make a difference, help cure disease, transform medicine, and improve human health? Do you love designing and building resilient distributed systems, troubleshooting complex workflows, partnering with stakeholders on product discovery, and working in a highly collaborative environment

Support the delivery of high quality technical standards, by supporting projects through the product approval process Design, Develop and Maintain open source implementations for approved GA4GH technical standards, including APIs and new bioinformatics file formats. Design and Develop software to support the implementation of GA4GH technical standards worldwide, such as t

Contribute to high throughput data production efforts by generating large scale cell based assay data in a fast paced, production oriented setting. Perform cell culture on up to 20 cell lines in parallel, with accurate monitoring for contamination and cell line fidelity as well as performing standard molecular biology procedures. Support in maintaining high quality data p

Train, develop and lead a team of professionals responsible for general accounting, reporting, tax, treasury operations and commercial banking, payroll, who manage the financial operations. Manage matrixed reporting for accounts payable and billing & collections, with a strong focus on ensuring cross team collaboration. Oversee the external financial statement and ERISA a

Establish procedures for tissue culture based experiments that involve measuring different phenotypic readouts (RNA, protein, reporter, viability, etc.) following chemical and genetic perturbations in both cell lines and primary iPSC derived neuronal cell models. Execute high throughput genome scale CRISPR modifier screens. Execute high throughput chemical modifier screen

Extensive experience in mammalian tissue culture. Establish procedures for tissue culture based experiments that involve measuring different phenotypic readouts (RNA, protein, reporter, viability, etc.) following chemical and genetic perturbations in both cell lines and primary patient derived cell models. Develop novel functional genomic, phenotypic, and biochemical assa

The Broad Institute of MIT & Harvard is an amazing place we apply our deep knowledge of human genetics to empower a revolution in biomedicine and accelerate the pace at which the world conquers disease. Through our partnerships with MIT, Harvard, and the Harvard teaching hospitals, we've become a worldwide hub of cutting edge biomedical science. The Broad was founded to e

Description & Requirements Postdoc The successful candidate will join an exciting project looking at in vivo mechanisms of bacterial pathogenesis by studying pathogen host interactions. In particular, the research will focus on 1) Host and pathogen genetic requirements for bacterial survival in vivo; 2) Identifying essential functions and small molecule tools with which t

Description & Requirements The Eric and Wendy Schmidt Center at the Broad Institute of MIT and Harvard is seeking exceptional postdoctoral associates to join this endowed center. The Schmidt Center's mission is to create the theoretical, computational and algorithmic paradigms that will enable us to understand the programs of life and how they connect across scales, from

Description & Requirements The Eric and Wendy Schmidt Center at the Broad Institute of MIT and Harvard is seeking exceptional postdoctoral associates to join this endowed center. The Schmidt Center's mission is to create the theoretical, computational and algorithmic paradigms that will enable us to understand the programs of life and how they connect across scales, from

Developing Data Driven Integration Techniques Collaborate with team members to design and implement novel data driven integration techniques for resolving inconsistencies in cell type classification across multiple modalities. Utilize advanced machine learning algorithms to establish objective criteria for cell classification based on similarity across data sets. Enhancin